Dr Marto joined the Dana-Farber Cancer Institute in 2004 where he is currently a Principle Investigator in the Departments of Cancer Biology and Oncologic Pathology. In addition, he holds a joint appointment as Associate Professor of Pathology at the Brigham and Women‚Äôs Hospital and Harvard Medical School.
Dr Marto also serves as Director of the Blais Proteomics Center at the Dana-Farber. Dr Marto uses mass spectrometry as a primary discovery tool to understand how genomic alterations, environmental insults, or the action of small molecule chemical probes impact the functional proteome, including protein post-translational modifications, biochemical complexes, signaling pathways, or how they manifest en masse as phenotypic or disease signatures.
Dr Marto's research is further enabled by development of advanced chromatographic separation platforms which provide improved peptide detection and quantification, and support genome-scale interrogation of mammalian proteomes. In addition, his lab builds open-source computation tools that facilitate interrogation of mass spectrometry data across the full spectrum of scientific inquiry, from the underlying instrumentation to interpretation of quantitative proteomic data in the context of biological pathways. His research program represents a productive convergence of biology, computation, and analytical science.
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Speaker for Keynote Lecture: Adventures in Multidimensional Fractionation for Quantitative Proteomics on September 28